3rd versus 16th in the table may not stand out as a 'big clash' - But this could just be a significant one come the end of the season.
If Leeds can salvage anything from a slow start marred by boardroom upheaval, this could be the night the turnaround takes hold.
Last week the news supporters wanted to hear went through; the takeover by Dubai-based GFH Capital was approved, with Ken Bates on borrowed time as chairman until a planned departure at the end of the season.
They got their feet in the door quickly enough to secure the loan deals of Jerome Thomas and Alan Tate from West Brom and Swansea ahead of last week's deadline, and the feelgood factor helped them upset the form book at the weekend.
Both players started as Leeds won their first game in seven, against then league leaders Crystal Palace of all people, inflicting a first defeat on new Eagles manager Ian Holloway.
With another home game against a top three side tonight, Leicester City, Elland Road will be rocking full of new-found belief.
For if Saturday was the day their season showed signs of turning around, tonight is the night the charge upwards really begins.
If they lose, then the joy from Saturday will somewhat evaporate. Leeds need to put together an unbeaten run, and following up their big win is of utmost importance. They will send a message to the rest of the league that the weekend was not a one-off result, and that they are looking to get back among the big boys.
A draw wouldn't be awful, but draws don't count for much in the Championship, where three points can see you leap three places in the league table.
It certainly will not be easy, Leicester have won their last two - including a 6-0 demolition of Ipswich, and have lost just twice in 10 games, but infallible they are not, as their 2-1 loss to Watford earlier this month showed.
Leeds have Jason Pearce suspended in defence, along with Luke Varney, although the latter has contributed just the one goal in attack this season, so he won't be overly missed.
They will have to reverse their fortunes against Leicester though, they have beaten the Foxes just one in the last 10 meetings between the sides. If there was ever a night to put that right, tonight was it.
If they can knock off the second promotion chaser in four days, and with a cup quarter final against Chelsea to look forward to, suddenly the signs of the good times coming back to Elland Road may not be so far away.
Can Leeds win tonight? Do you believe they can go on an unbeaten run?
image: © Chris Robertshaw