Manchester United, Manchester City, Everton, Chelsea and Arsenal are backed to progress while Stoke, Fulham, Aston Villa and a shock exit for Liverpool are our potential Premier League victims.
Here they are…
Millwall v Aston Villa: 2-1
After plummeting out of the Capital One Cup in such a fashion to Bradford City earlier in the week recovering both physically and mentally for a Friday night FA Cup fixture at The Den seems a very difficult task for Paul Lambert’s young team.
Stoke v Manchester City: 0-2
Stoke will certainly be no pushovers but the Champions will be too strong in this all Premier League tie at The Britannia.
Norwich v Luton: 4-1
It is great to see Luton this far in the competition and a trip to Carrow Road will be a great occasion for the side. However I fear the dream stops here as Norwich should be too strong for their non-league opponents.
Macclesfield v Wigan: 1-3
Roberto Martinez may be having nightmares ahead of this game as it certainly looks a potential mammoth banana skin in the making. As much as I think The Silkmen will give it their all again Premier League class should prevail.
Derby v Blackburn: 2-2
Not much between these two Championship sides and that should hopefully produce an exciting encounter. Going to say Blackburn may edge it but to be honest it could go either way. Therefore logic dictates a replay at Ewood Park.
Hull v Barnsley: 4-0
Hull are flying high in the Championship and Steve Bruce should have no problems in this all Championship Yorkshire derby.
Middlesbrough v Aldershot: 3-0
It is a long old trip from Hampshire to Teesside but I fear it may be an even longer one back for The Shots.
Brighton v Arsenal: 1-2
One of the most highly anticipated fixtures of the round sees Arsenal travel to the Amex to take on the entertaining Seagulls. It depends on which Arsenal turn-up; the inept Bradford fodder or the scything West Ham killers.
Reading v Sheffield United: 1-1
Can see Reading only taking this half seriously considering their current relegation battles so The Blades may fancy their chances of taking Premier League opposition back to Bramall Lane.
Huddersfield v Leicester: 1-3
Huddersfield have just sacked Simon Grayson and while talk of Nigel Adkins imminent appointment is mounting The Foxes should capitalise in this tie.
QPR v MK Dons: 2-1
MK Dons are one of the lower league teams most Premier League managers probably don’t want to face but Harry Redknapp has Loic Remy at his disposal and the Dons defenders may have never played against such quality.
Bolton v Everton: 1-3
At first I considered a cup shock for this game but considering David Moyes desire to win silverware this season I sense he will leave nothing to chance at the Reebok.
Manchester United v Fulham: 3-0
United will not want to inconvenience of playing another replay this time round and after a rejuvenating time in the sun of Dubai they should make light work of Fulham.
Brentford v Chelsea: 0-2
Griffin Park; the only football stadium with a pub built in all four corners of the grounds and The Bees may need a half-a-mild or two if Chelsea bring their A-game across London.
Leeds v Tottenham: 1-1
Neil Warnock loves the FA Cup and while Spurs on paper should be comfortable winners I can see Leeds just holding out for a draw.
Oldham v Liverpool: 2-1
Here it is. My one and only big shock suggestion and a big shock it would be indeed. Oldham are near the relegation mark in League One but that position does not tell of their potential. If Liverpool go to Boundary Park with the wrong attitude The Lactics WILL punish them.
Do you think there could be an FA Cup shock or two this weekend?